Latest Research
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28 Aug
Researchers Elucidate Molecular Mechan…
Genome stability and integrity is essential for the survival of all organisms. However, due to the endogenous metabolites and environmental agents (such as UV light or chemical exposure), DNA damage constantly happens and posts a threat. DNA glycosylase is a DNA-binding protein responsible for repairing the DNA damage. It remains a puzzle how glycosylase can efficiently and accurately recognize DNA lesions among millions and billions of normal base pairs in the genome. It has been hypothesized that glycosylase accomplishes this task by an alternating search between two diffusion modes: a hig…
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21 Jul
Wei Xie’s group and Bing Zhu’s group…
A joint team led by Dr. Wei Xie from School of Life Sciences of at Tsinghua University and Dr. Bing Zhu from Institute of Biophysics at Chinese Academy of Sciences, has revealed how the DNA methylome
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30 Jun
Xuerui Yang’s group at Tsinghua and D…
A collaborative work by Dieter Wolf’s group at Xiamen University and Xuerui Yang’s group at Tsinghua has led to a new research article, “eIF3 Associates with 80S Ribosomes to Promote Translation Elong
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24 Jun
Wei Xie’s group and Yi-Liang Miao’s …
A joint team led by Prof. Wei Xie at Tsinghua University and Prof. Yi-Liang Miao at Huazhong Agricultural University has revealed how genome architecture is reprogrammed during somatic cell nuclear tr
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10 Apr
The Ge lab identified a translocation …
Over evolution, members of the biology kingdom have acquired protein secretion as a fundamental mechanism for intercellular communication. In eukaryotes, majority of the secretory proteins contain a s
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31 Mar
Xinquan Wang and Linqi Zhang groups re…
On March 30, 2020, a research paper entitled “Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor” was published online in？Nature as “Accelerated Article Preview”？by t
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26 Mar
International study identifies gene li…
BD is a severe neuropsychiatric disorder characterized by intermittent episodes of mania and depression. However, the origin of BD has remained enigmatic, mainly because genetic animal models based on
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26 Mar
Songhai Shi and Hang Shi's groups unco…
On March 25th, a research paper entitled “Centrosome Anchoring Regulates Progenitor Properties and Cortical formation” was published online in Nature by the groups of Dr. Song-Hai Shi and Dr. Hang Shi
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17 Dec
Wei Xie’s group published a research …
Prof. Wei Xie’ group at Tsinghua University has published an article in Nature Genetics, entitled ‘Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency’ on D
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13 Dec
Wei Xie’s group and Antoine H.F.M. Pe…
A joint team led by Prof. Wei Xie at Tsinghua University and Prof. Antoine H.F.M. Peters from Friedrich Miescher Institute for Biomedical Research has published a research paper in Molecular Cell on D