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Xiaoxuan Jia Ph.D.

Associate Professor

2005 Tsinghua University, China, B.S.

2012 Albert Einstein College of Medicine, US, Ph.D.

2012-2015 Department of Brain and Cognitive Sciences; McGovern Institute for Brain Research, MIT, US, Postdoctoral Associate

2016-2022 Allen Institute, US, Senior Scientist

2022-present School of Life Sciences, Tsinghua University, China, Associate Professor

2022-present Center for Life Sciences & IDG/McGovern Institute for Brain Research at Tsinghua University, China, Principal Investigator

● Research interest：

We seek to understand the neural computations underlying flexible perception and cognition. Our research lies at the intersection of systems, computational, and cognitive neuroscience. In particular, we are interested in understanding how visual sensory information is represented and propagated in the mammalian brain. Our approach combines large-scale in vivo electrophysiology, closed-loop brain-machine interface (BMI), machine learning, neural network modeling and quantitative (online) human psychophysics.

Lab website: https://jiaxx.github.io/

● Selected publications：

1. Jia X*, Siegle JH, Durand S, Heller G, Ramirez T, Koch C , Olsen SR^†. (2022) Multi-regional module-based signal transmission in mouse visual cortex. Neuron doi: https://doi.org/10.1016/j.neuron.2022.01.027

2. Jia X*, Hong H, DiCarlo JJ. (2021) Unsupervised changes in core object recognition behavioral performance are accurately predicted by unsupervised neural plasticity in inferior temporal cortex. eLife 2021;10:e60830 (Simons foundation global brain recommended)

3. Siegle JH*, Jia X*, Durand S, Gale S, Bennett C, Graddis N, Heller G, ... Olsen SR*, Koch C. (2021) A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas. Nature 592, 86-92

4. Jia X*, Siegle JH, Bennett C, Gale SD, Denman DJ, Koch C, Olsen SR*. (2019) High-density extracellular probes reveal dendritic backpropagation and facilitate neuron classification. Journal of neurophysiology 121 (5), 1831-1847

5. Billeh YN, Cai B, Gratiy SL, Dai K, Iyer R, Gouwens RW, Abbasi-Asl R, Jia X, Siegle JH, Olsen SR, Koch C, Mihalas S, Arkhipov A*. (2019) Systematic Integration of Structural and Functional Data into Multi-Scale Models of Mouse Primary Visual Cortex. Neuron. NEURON-D-19-01027

6. Garrett ME, Manavi S, Roll K, Ollerenshaw DR, Groblewski PA, Kiggins J, Jia X, Casal L, Mace K, Williford A, Leon A, Mihalas S, Olsen SR*. (2020) Experience shapes activity dynamics and stimulus coding of VIP inhibitory and excitatory cells in visual cortex. eLife 2020;9:e50340

7. Jia X*, Xing D, Kohn A. (2013) No consistent relationship between gamma power and peak frequency in macaque primary visual cortex. Journal of Neuroscience 33 (1), 17-25

8. Jia X*, Tanabe S, Kohn A. (2013) Gamma and the coordination of spiking activity in early visual cortex. Neuron 77 (4), 762-774 (Faculty 1000 recommended)

9. Jia X*, Smith MA, Kohn A. (2011) Stimulus selectivity and spatial coherence of gamma components of the local field potential, Journal of Neuroscience 31 (25), 9390-9403

10. Smith MA^†, Jia X, Zandvakili A, Kohn A. (2012) Laminar dependence of neuronal correlation in macaque V1. Journal of Neurophysiology. DOI:10.1152/jn.00846.2012.

11. Jia X^†, Kohn A. (2011) Gamma rhythms in the brain. PLoS Biology. 9(4):e1001045.

● Award：

17th Julius Marmur Research Award

● Contact information：

Email： jiaxx@mail.tsinghua.edu.cn

Address：Biomedical Building Room B402, Tsinghua University, Beijing, China, 100084