Xin LIANG     Ph.D.

Associate Professor

1999-2003 B.Sc.     Shanghai Jiao Tong University
2003-2007 Ph.D.     Shanghai Jiao Tong University
2008-2014 Postdoctoral fellow   MPI-CBG
2015-2019 Max-Planck Partner Group Leader Tsinghua University
2015-  Assistant Professor, Associate Professor Tsinghua University

Research interest

1. Microtubule dynamics (cell biology)
2. Molecular basis of microtubule-based mechanotransduction in Drosophila

Courses offered

Physiology (undergraduate), 48 lectures

Selected publications

1. Xie, S. *, J. Li, S. Sun, W. Chen, H. Cheng, Y. Song, Y. Li, M. Liu, X. Zhu, X. Liang*, and J. Zhou*. 2022. TUBright: A Peptide Probe for Imaging Microtubules. Anal Chem.

2. Diao, L., M.Y. Liu, Y.L. Song, X. Zhang, X. Liang*, and L. Bao*. 2022. alpha1A and alpha1C form microtubules to display distinct properties mainly mediated by their C-terminal tails. J Mol Cell Biol. 13:864-875.

3. Shree, S., S. Sutradhar, O. Trottier, Y. Tu, X. Liang, and J. Howard*. 2022. Dynamic instability of dendrite tips generates the highly branched morphologies of sensory neurons. Sci Adv. 8:eabn0080.

4. Sun, L., L. Cui, Z. Liu, Q. Wang, Z. Xue, M. Wu, T. Sun, D. Mao, J. Ni, J.C. Pastor-Pareja, and X. Liang*. 2021. Katanin p60-like 1 sculpts the cytoskeleton in mechanosensory cilia. J Cell Biol. 220.

5. Liao, M., X. Liang, and J. Howard. 2021. The narrowing of dendrite branches across nodes follows a well-defined scaling law. Proc Natl Acad Sci U S A. 118.

6. Li, S., K.Y. Wan, W. Chen, H. Tao, X. Liang*, and J. Pan*. 2020. Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in Chlamydomonas. Elife. 9.

7. Song, Y., Y. Zhang, Y. Pan, J. He, Y. Wang, W. Chen, J. Guo, H. Deng, Y. Xue, X. Fang, and X. Liang*. 2020. The microtubule end-binding affinity of EB1 is enhanced by a dimeric organization that is susceptible to phosphorylation. J Cell Sci. 133.

8. Liang, X*. 2019. Microtubule nucleation and dynamic instability in interphase fission yeast. J Mol Cell Biol. 11:941-943.

9. Sun, L., Y. Gao, J. He, L. Cui, J. Meissner, J.M. Verbavatz, B. Li, X. Feng, and X. Liang*. 2019a. Ultrastructural organization of NompC in the mechanoreceptive organelle of Drosophila campaniform mechanoreceptors. Proc Natl Acad Sci U S A. 116:7343-7352.

10. Sun, T., Y. Song, J. Dai, D. Mao, M. Ma, J.Q. Ni, X. Liang, and J.C. Pastor-Pareja*. 2019b. Spectraplakin Shot Maintains Perinuclear Microtubule Organization in Drosophila Polyploid Cells. Dev Cell. 49:731-747 e737.

Awards

2015-               Max-Planck Partner Group Program

Contact information

Email: xinliang@tsinghua.edu.cn
Orcid ID: https://orcid.org/0000-0001-7915-8094/print